Immunoglobulin G4 (IgG4) is a member of many immunoglobulin G developed and secreted by effective B cells.
In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment.
The Fc segment bears a highly conserved N-glycosylation site.
Ig gamma-4 chain Fc region contains two constant regions of IgG4 H chain (CH2, CH3).
特徴
This protein carries no "tag".
The protein has a calculated MW of 25.8 kDa.
As a result of glycosylation, the protein migrates as 30-32 kDa under reducing (R) condition, and 28-30 kDa and 55-60 kDa under non-reducing (NR) condition (SDS-PAGE).
仕様
容量：200ug
Source：Human IgG4 Fc, Tag Free (IG4-H5205) is expressed from human 293 cells (HEK293). It contains AA Glu 99 - Lys 327 (Accession # P01861).
Species Reactivity：Human
Host：HEK293
Tag：Native
Exp Region：Glu 99 - Lys 327
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：P01861
Endotoxin：1.0 EU per μg
Purity：95%
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
