83-3846-57 Human IgG3 Fc Protein, Tag Free (MALS & SPR verified) 1mg IG3-H5200-1mg
特徴
- 背景
- Immunoglobulin G3 (IgG3) is a member of many immunoglobulin G developed and secreted by effective B cells.
- In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment.
- The Fc segment bears a highly conserved N-glycosylation site.
- Ig gamma-3 chain C region (IgG3-Fc / IGHG3) contains two constant regions of IgG3 H chain (CH2, CH3).
- 特徴
- This protein carries no "tag".
- The protein has a calculated MW of 31.2 kDa.
- The protein migrates as 35-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
- 容量:1mg
- Source:Human IgG3 Fc, Tag Free (IG3-H5200) is expressed from human 293 cells (HEK293). It contains AA Glu 99 - Lys 377 (Accession # P01860).
- Species Reactivity:Human
- Host:HEK293
- Tag:Native
- Exp Region:Glu 99 - Lys 377
- Format:Powder
- Conjugate:Unconjugated
- Swiss-Prot:P01860
- Endotoxin:1.0 EU per μg
- Purity:95%
- Buffer:Tris with Glycine, Arginine and NaCl, pH7.5
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