Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds.
Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport).
IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
特徴
This protein carries an Avi tag (Avitag) at the C-terminus.
The protein has a calculated MW of 28.4 kDa.
The protein migrates as 32-34 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：25ug
Source：Biotinylated Human IgG1 Fc, Avitag (IG1-H8213) is expressed from human 293 cells (HEK293). It contains AA Glu 99 - Lys 330 (Accession # P01857-1 ).
Species Reactivity：Human
Host：HEK293
Tag：C-Avi
Exp Region：Glu 99 - Lys 330
Format：Powder
Conjugate：Biotin-labeled
Swiss-Prot：P01857-1
Protein ID：BAC85237.1
Endotoxin：1.0 EU per μg
Purity：95%
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
