Interferon alpha/beta receptor 1 ( IFNAR1) is also known as Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1 (CRF2-1), Type I interferon receptor 1, IFNAR, which belongs to the type II cytokine receptor family.
IFNAR1 /IFNAR contains four fibronectin type-III domains.
IFNAR1 associates with IFNAR2 to form the type I interferon receptor.
IFNAR1 is receptor for interferons alpha and beta.
IFNAR1 can transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 73.8 kDa.
The protein migrates as 100-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human IFNAR1, Fc Tag (IF1-H5253) is expressed from human 293 cells (HEK293). It contains AA Lys 28 - Lys 436 (Accession # NP_000620).
Species Reactivity：Human
Host：HEK293
Tag：C-Fc
Exp Region：Lys 28 - Lys 436
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：P17181
Protein ID：NP_000620
Endotoxin：1.0 EU per μg
Purity：90%
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
