CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus.
NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation.
CD94 pairs with the NKG2 molecule as a heterodimer.
The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 40.4 kDa & 42.3 kDa.
The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：25ug
Source：Biotinylated Human NKG2A&CD94 Protein, Fc,Avitag (NC4-H82F5) is expressed from human 293 cells (HEK293). It contains AA Ala 113 - Leu 233 & Asp 57-Ile 179 (Accession # P26715-1 (NKG2A) & Q13241-1 (CD94)).
