Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family.
The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain.
Notably, the intracellular domain of phatases.
The extracellular domain sequence of human and mouse CD112R have 65.3% similarity.
CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 41.9 kDa.
The protein migrates as 50-58 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：25ug
Source：Biotinylated Human PVRIG Protein, Fc,Avitag (PVG-H82F9) is expressed from human 293 cells (HEK293). It contains AA Thr 41 - Asp 171 (Accession # Q6DKI7-1).
