Heparin-binding epidermal growth factor (EGF)-like growth factor (HBEGF) is a ligand for the EGF receptor (EGFR) and a critical molecular component to a number of normal physiological processes including but not limited to tissue injury and wound healing, reproduction, angiogenesis and recently, adipogenesis.
Misexpression of HB-EGF is linked to tumor formation and cancer including hepatocellular, pancreatic, gastric, breast, colon and melanoma, gliomas and glioblastomas.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 11.8 kDa.
The protein migrates as 16-23 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human HBEGF, His Tag (HBF-H52H3) is expressed from human 293 cells (HEK293). It contains AA Asp 63 - Leu 148 (Accession # Q99075-1).
