Glycoprotein A33 (GPA33) is also known as Cell surface A33 antigen, is a single-pass type I membrane protein which is expressed in normal gastrointestinal epithelium and in 95% of colon cancers.
GPA33 The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail.
The sequence of the extracellular region contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily, which contains.
GPA33 may play a role in cell-cell recognition and signaling.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 24.7 kDa.
The protein migrates as 33-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Mouse GPA33, His Tag (GP3-M5225) is expressed from human 293 cells (HEK293). It contains AA Leu 22 - Ile 235 (Accession # Q9JKA5-1).
