This protein is involved in the misfolding of normal prion proteins in the cell membrane to the infectious prion form.
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains.
Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage.
These proteins may play a role in the control of cell division and growth regulation.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 57.5 kDa.
The protein migrates as 60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量:100ug
Source:Mouse Glypican 1, His Tag (GP1-M52H7) is expressed from human 293 cells (HEK293). It contains AA Asp 24 - Ser 529 (Accession # Q9QZF2-1).