This protein is involved in the misfolding of normal prion proteins in the cell membrane to the infectious prion form.
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains.
Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage.
These proteins may play a role in the control of cell division and growth regulation.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 82.5 kDa.
The protein migrates as 90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human Glypican 1, Fc Tag (GP1-H5254) is expressed from human 293 cells (HEK293). It contains AA Asp 24 - Ser 530 (Accession # P35052-1).
Species Reactivity：Human
Host：HEK293
Tag：C-Fc
Exp Region：Asp 24 - Ser 530
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：P35052-1
Protein ID：NP_002072.2
Endotoxin：1.0 EU per μg
Purity：90%
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
