Growth differentiation factor 8 (GDF8), also known as myostatin, is a unique member of the transforming growth factor-β superfamily that is expressed in human granulosa cells and has important roles in regulating a variety of ovarian functions.
GDF8 acts as a negative regulator of skeletal muscle growth and differentiation.
In addition to the expression in the musculoskeletal system, GDF8 is also expressed in various tissues, including the reproductive system.
特徴
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 42.0 kDa.
The protein migrates as 35 kDa and 45-50 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：50ug
Source：Human latent GDF-8, His Tag (GD8-H5243) is expressed from human 293 cells (HEK293). It contains AA Asn 24 - Ser 375 (Accession # O14793-1).
