CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus.
NKG2C/CD159c is used as a receptor for NK cells and some cytotoxic T cells to recognize MHC class I HLA-E molecules.
CD94 pairs with the NKG2 molecule as a heterodimer.
The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 57.1 kDa.
The protein migrates as 65-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human NKG2C&CD94, Fc Tag (NC4-H5258) is expressed from human 293 cells (HEK293). It contains AA Ile 94 - Leu 231 (NKG2C) & Asp 57 - Ile 179 (CD94) (Accession # P26717-1 (NKG2C) & Q13241-1 (CD94)).
Species Reactivity：Human
Host：HEK293
Tag：C-Fc
Exp Region：Ile 94 - Leu 231 (NKG2C) & Asp 57 - Ile 179 (CD94)
