83-3844-42 Human MICA Protein, Fc Tag 100ug MIA-H5253-100ug
特徴
- 背景
- MHC class I polypeptide-related sequence A (MICA) belongs to the MHC class I family and MIC subfamily.
- MICA contains one Ig-like C1-type (immunoglobulin-like) domain.
- Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin.
- MICA acts as a stress-induced self-antigen that is recognized by gamma delta T-cells.
- MICA is ligand for the KLRK1/NKG2D receptor.
- MICA bind to KLRK1 leads to cell lysis.
- 特徴
- This protein carries a human IgG1 Fc tag at the C-terminus.
- The protein has a calculated MW of 59.3 kDa.
- The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
- 容量：100ug
- Source：Human MICA, Fc Tag (MIA-H5253) is expressed from human 293 cells (HEK293). It contains AA Glu 24 - Gln 308 (Accession # AAH16929.1).
- Species Reactivity：Human
- Host：HEK293
- Tag：C-Fc
- Exp Region：Glu 24 - Gln 308
- Format：Powder
- Conjugate：Unconjugated
- Swiss-Prot：Q29983-1 (K148E)
- Protein ID：AAH16929.1
- Endotoxin：1.0 EU per μg
- Purity：95%
- Buffer：PBS, pH7.4
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