83-3843-89　Human ENPP-2 / Autotaxin Protein, His Tag （active enzyme） 50ug　EN2-H5241-50ug

特徴

• 背景
• Autotaxin also known as ectonucleotide pyrophosphatase / phosphodiesterase family member 2 (E-NPP 2 or ENPP2), Extracellular lysophospholipase D (LysoPLD), Autotaxin (ATX or ATX-X), which belongs to the nucleotide pyrophosphatase / phosphodiesterase family.
• ENPP2 contains two SMB (somatomedin-B) domains.
• ENPP2 hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids.
• ENPP2 can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility.
• ENPP2 stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein.
• 特徴
• This protein carries a polyhistidine tag at the N-terminus.
• The protein has a calculated MW of 94.5 kDa.
• The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE).

仕様

• 容量：50ug
• Source：Human ENPP-2, His Tag (EN2-H5241) is expressed from human 293 cells (HEK293). It contains AA Asp 49 - Ile 863 (Accession # NP_001035181).
• Species Reactivity：Human
• Host：HEK293
• Tag：N-6×His
• Exp Region：Asp 49 - Ile 863
• Format：Powder
• Conjugate：Unconjugated
• Swiss-Prot：Q13822
• Protein ID：NP_001035181
• Endotoxin：1.0 EU per μg
• Purity：95%
• Buffer：50 mM Tris, 150 mM NaCl, pH 7.5
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