The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands.
The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4).
Mutations affecting EGFR expression or activity could result in cancer.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 95.3 kDa.
The protein migrates as 116-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Rhesus macaque EGF R, Fc Tag (EGR-C5252) is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Ser 645 (Accession # P55245).
Species Reactivity：Rhesus macaque
Host：HEK293
Tag：C-Fc
Exp Region：Leu 25 - Ser 645
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：P55245
Endotoxin：1.0 EU per μg
Purity：95%
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
