Ephrin-A3 (Ephrin A3) is also known as EFL-2, EHK1 ligand, EHK1-L, EPH-related receptor tyrosine kinase ligand 3, EFL2, EPLG3 and LERK3,which comprises the largest subfamily of receptor protein-tyrosine kinases (RTKs), and has been involved in a variety of biological processes, especially in the nervous system and in erythropoiesis, such as axon guidance and topographic map formation, synaptic plasticity, angiogenesis, and meanwhile have possible contributions to tumor growth and metastasis.
Ephrin A3 is cell surface GPI-bound ligand for Eph receptors and belongs to the family of receptor tyrosine kinases.
Ephrin can bind promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 48.4 kDa.
The protein migrates as 60-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：200ug
Source：Human Ephrin-A3, Fc Tag (EA3-H5258) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Ser 213 (Accession # AAI10407).
Species Reactivity：Human
Host：HEK293
Tag：C-Fc
Exp Region：Gln 23 - Ser 213
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：P52797
Protein ID：AAI10407
Endotoxin：1.0 EU per μg
Purity：90%
Buffer：100 mM Glycine, 150 mM Nacl, 25 mM Arginine, 50 mM Tris, pH7.5
