83-3842-63　Human CD300c / LMIR2 Protein, His Tag 100ug　CDC-H5224-100ug

特徴

• 背景
• CMRF35-like molecule 6 (CLM-6) is also known as CD300 antigen-like family member C, CMRF35-A1, Immunoglobulin superfamily member 16 (IgSF16) , CD antigen CD300c, which belongs to the CD300 family.
• CLM-6 contains one Ig-like V-type (immunoglobulin-like) domain.
• CD300a/c RNA and surface expression were downregulated after stimulation of plasmacytoid dendritic cells (pDCs) with TLR7 and TLR9 ligands.
• Exogenous interferon (IFN)-alpha down-regulated CD300a/c expression.
• CD300a and CD300c play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs.
• CD300a and CD300c are indistinguishable on the surface of NK cells.
• 特徴
• This protein carries a polyhistidine tag at the C-terminus.
• The protein has a calculated MW of 18.67 kDa.
• The protein migrates as 26-43 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.