Scavenger receptor cysteine-rich type 1 protein M130 (CD163) is also known as hemoglobin scavenger receptor, which is a scavenger receptor for the hemoglobin-haptoglobin complex.
CD163 has also been shown to mark cells of monocyte/macrophage lineage.
A soluble form of the receptor exists in plasma, commonly denoted sCD163.
sCD163 is generated by ectodomain shedding of the membrane bound receptor.
sCD163 is upregulated in a large range of inflammatory diseases including liver cirrhosis, type 2 diabetes, macrophage activation syndrome, Gaucher's disease, sepsis, HIV infection, rheumatoid arthritis and Hodgkin Lymphoma.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 110.4 kDa.
The protein migrates as 135-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human CD163, His Tag (CD3-H52E8) is expressed from human 293 cells (HEK293). It contains AA Ser 42 - Ser 1045 (Accession # Q86VB7).
