CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus.
NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation.
CD94 pairs with the NKG2 molecule as a heterodimer.
The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.
特徴
This protein carries a mouse IgG2a Fc tag at the C-terminus.
The protein has a calculated MW of 55.5 kDa.
The protein migrates as 65-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human NKG2A&CD94, Mouse IgG2a Fc Tag (NC4-H5253) is expressed from human 293 cells (HEK293). It contains AA Ala 113 - Leu 233 (NKG2A) & Asp 57 - Ile 179 (CD94) (Accession # P26715-1 (NKG2A) & Q13241-1 (CD94)).
Species Reactivity：Human
Host：HEK293
Tag：C-mFc(mIgG2a)
Exp Region：Ala 113 - Leu 233 (NKG2A) & Asp 57 - Ile 179 (CD94)
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：P26715-1 (NKG2A) & Q13241-1 (CD94)
Protein ID：NP_002250.1 (NKG2A) &
Endotoxin：0.1 EU per μg
Purity：95%
Buffer：50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
