T-cell surface antigen CD2 is also known as Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5 and SRBC, is a single-pass type I membrane protein found on the surface of T cells and natural killer (NK) cells.
CD2 is a member of the immunoglobulin superfamily.
CD2 / SRBC interacts with other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3 / CD58) in humans, or CD48 in rodents, which are expressed on the surfaces of other cells.
In addition to its adhesive properties, CD2 also acts as a co-stimulatory molecule on T and NK cells.
CD2 is a specific marker for T cells and NK cells, and can therefore be used in immunohistochemistry to identify the presence of such cells in tissue sections.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 47.7 kDa.
The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human CD2, Fc Tag (CD2-H5258) is expressed from human 293 cells (HEK293). It contains AA Lys 25 - Asp 209 (Accession # AAH33583).
Species Reactivity：Human
Host：HEK293
Tag：C-Fc
Exp Region：Lys 25 - Asp 209
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：P06729-1(H266Q)
Protein ID：AAH33583
Endotoxin：1.0 EU per μg
Purity：95%
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
