ALK-7 (Activin receptor-like kinase 7) is also known as Activin receptor type-1C, ACTR-IC, ACVR1C.
Serine/threonine protein kinase which forms a receptor complex on ligand binding.
The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases.
Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3.
Receptor for activin AB, activin B and NODAL.
Plays a role in cell differentiation, growth arrest and apoptosis.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 11.9 kDa.
The protein migrates as 15-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human ALK-7, His Tag (AL7-H52H5) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Glu 113 (Accession # Q8NER5-1).
