Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules.
In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity.
Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 86.6 kDa.
The protein migrates as 100-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Cynomolgus Cadherin-17, His Tag (CA7-C52H4) is expressed from human 293 cells (HEK293). It contains AA Lys 30 - Thr 792 (Accession # A0A2K5X8I8-1).
Species Reactivity：Cynomolgus
Host：HEK293
Tag：C-10×His
Exp Region：Lys 30 - Thr 792
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：A0A2K5X8I8-1
Endotoxin：1.0 EU per μg
Purity：85%
Buffer：20 mM Tris, 150 mM NaCl, 0.5 M Arginine, pH8.0
