Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a a type II classical cadherin from the cadherin superfamily.
Cadherins are calcium-dependent cell adhesion proteins.
They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
CDH6 / KCAD contains five cadherin domains.
CDH6 is highly expressed in brain, cerebellum, and kidney.
Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The Human Cadherin-6 will be further processed into mature form (Ser 54 - Ala 615).The protein has a calculated MW of 92.8 kDa.
The protein migrates as 100-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human Cadherin-6 Protein, Fc Tag (CA6-H5258) is expressed from human 293 cells (HEK293). It contains AA Thr 19 - Ala 615 (Accession # P55285-1).
Species Reactivity：Human
Host：HEK293
Tag：C-Fc
Exp Region：Thr 19 - Ala 615
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：P55285-1
Protein ID：NP_004923.1
Endotoxin：1.0 EU per μg
Purity：90%
Buffer：50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
