Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a a type II classical cadherin from the cadherin superfamily.
Cadherins are calcium-dependent cell adhesion proteins.
They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
CDH6 / KCAD contains five cadherin domains.
CDH6 is highly expressed in brain, cerebellum, and kidney.
Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 67.9 kDa.
The protein migrates as 80-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Cynomolgus / Rhesus macaque Cadherin-6, His Tag (CA6-C52H3) is expressed from human 293 cells (HEK293). It contains AA Thr 22 - Gly 614 (Accession # G7MUQ7-1). In the region Thr 22 - Gly 614, the AA sequence of Cynomolgus and Rhesus macaque Cadherin-6 are homologus.
