Leukocyte differentiation antigen CD84 is also known as SLAM family member 5 (SLAMF5), which belongs to immunoglobulin (Ig) superfamily.
CD84 / SLAMF5 contains one Ig-like C2-type (immunoglobulin-like) domain.
CD84 plays a role as adhesion receptor functioning by homophilic interactions and by clustering.
CD84 / SLAMF5 increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process.
Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway.
特徴
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 26.5 kDa.
The protein migrates as 40-50 KDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：200ug
Source：Biotinylated Human CD84, His,Avitag (CD4-H82E5) is expressed from human 293 cells (HEK293). It contains AA Lys 22 - Gly 225 (Accession # Q9UIB8-3).
