Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains.
The LAG3 gene contains 8 exons.
The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4.
LAG3 /CD223 involved in lymphocyte activation.
LAG3 /CD223 binds to HLA class-II antigens.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 47.1 kDa.
The protein migrates as 55-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human LAG-3 Protein, His Tag (LA3-H522a) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Leu 450 (Accession # P18627-1).
