Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains.
The LAG3 gene contains 8 exons.
The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4.
LAG3 /CD223 involved in lymphocyte activation.
LAG3 /CD223 binds to HLA class-II antigens.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 73.0 kDa.
The protein migrates as 85-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Cynomolgus LAG-3, Fc Tag (LA3-C5252) is expressed from human 293 cells (HEK293). It contains AA Ala 18 - His 449 (Accession # XP_005570011.1).
Species Reactivity：Cynomolgus
Host：HEK293
Tag：C-Fc
Exp Region：Ala 18 - His 449
Format：Powder
Conjugate：Unconjugated
Protein ID：XP_005570011.1
Endotoxin：1.0 EU per μg
Purity：90%
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
