SLAM family member 7 (SLAMF7) is also known as CD2-like receptor-activating cytotoxic cells (CRACC), Membrane protein FOAP-12, CD antigen CD319, Novel Ly9, Protein 19A, which is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors.
SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea.
Isoform 1 of SLAMF7 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway.
May play a role in lymphocyte adhesion.
Isoform 3 of SLAMF7 does not mediate any NK cell activation.
特徴
This protein carries a mouse IgG2a Fc tag at the C-terminus.
The protein has a calculated MW of 49.4 kDa.
The protein migrates as 55-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Mouse SLAMF7 Protein, Mouse IgG2a Fc Tag (SL7-M5252) is expressed from human 293 cells (HEK293). It contains AA Ala 22 - Gly 224 (Accession # Q8BHK6-1).
