Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87.
PLAUR contains three UPAR/Ly6 domains.
U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain.
PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1.
PLAUR / UPAR acts as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation.
U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.
特徴
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 35.0 kDa.
The protein migrates as 45-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：200ug
Source：Biotinylated Human uPAR, His,Avitag (UPR-H82E7) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Arg 303 (Accession # Q03405-1).
