The transmembrane protein, TCR, comprise of two disulphide-linked polypeptide chains: a α and β chain, a γ and δ chain.
Each polypeptide chain consists of a variable and a constant region.
TRBC1 is the constant region of T-cell receptor (TCR) beta chain.
TRBC1 is presented on the surface of T cell and recognized peptide-major histocompatibility (MH) (pMH) that are displayed by antigen presenting cells (APC).
TRBC1 is participate in an adaptive immune response and has been well-studied in T cell therapy.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 18.2 kDa.
The protein migrates as 20 kDa and 24 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量:100ug
Source:Human TRBC1, His Tag (TR1-H52H4) is expressed from human 293 cells (HEK293). It contains AA Asp 1 - Ala 144 (Accession # P01850-1).