83-3834-40 Mouse uPAR / PLAUR Protein, His Tag （SPR verified） 1mg UPR-M52H3-1mg
特徴
- 背景
- Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87.
- PLAUR contains three UPAR/Ly6 domains.
- U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain.
- PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1.
- PLAUR / UPAR acts as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation.
- U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.
- 特徴
- This protein carries a polyhistidine tag at the C-terminus.
- The protein has a calculated MW of 31.7 kDa.
- The protein migrates as 45-63 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
- 容量：1mg
- Source：Mouse uPAR, His Tag (UPR-M52H3) is expressed from human 293 cells (HEK293). It contains AA Leu 24 - Pro 296 (Accession # P35456-1).
- Species Reactivity：Mouse
- Host：HEK293
- Tag：C-10×His
- Exp Region：Leu 24 - Pro 296
- Format：Powder
- Conjugate：Unconjugated
- Swiss-Prot：P35456-1
- Protein ID：NP_035243.1
- Endotoxin：1.0 EU per μg
- Purity：85%
- Buffer：PBS, pH7.4
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