Galectin-4 (Gal-4), also known as L36LBP (L-36 lactose-binding protein).
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions.
Galectin-4 expression is concentrated within microvilli in the gastrointestinal epithelium, where it can interact with CD3 and bind activated T cells in the lamina propria during intestinal inflammation.
LGALS4 is an S-type lectin that is strongly underexpressed in colorectal cancer.
特徴
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 38.1 kDa.
The protein migrates as 40-44 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human Galectin-4, His Tag (GA4-H5246) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ile 323 (Accession # P56470-1).
Species Reactivity：Human
Host：HEK293
Tag：N-9×His
Exp Region：Met 1 - Ile 323
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：P56470-1
Protein ID：NP_006140.1
Endotoxin：1.0 EU per μg
Purity：95%
Buffer：50 mM HEPES, 150 mM NaCl, 5 mM EDTA, 2 mM TCEP, pH7.4
