Leukocyte immunoglobulin-like receptor subfamily B member 3 is also known as LILRB3,ILT-5 or CD85a.
LILRB3 plays an role as receptor for class I MHC antigens, which activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor.
LILRB3 and LILRA6 represent a pair of inhibitory/activating receptors with identical extracellular domains and unknown ligands.
LILRB3 can mediate inhibitory signaling via immunoreceptor tyrosine-based inhibition motifs in its cytoplasmic tail whereas LILRA6 can signal through association with an activating adaptor molecule, FcRγ.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 72.8 kDa.
The protein migrates as 90-115 kDa under reducing (R) condition, and 150 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human LILRB3, Fc Tag (CDA-H5250) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Glu 443 (Accession # AAB68668 (P288R)).
Species Reactivity：Human
Host：HEK293
Tag：C-Fc
Exp Region：Gly 24 - Glu 443
Format：Powder
Conjugate：Unconjugated
Protein ID：AAB68668 (P288R)
Endotoxin：1.0 EU per μg
Purity：95%
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
