83-3834-08 ［取扱停止］Human uPAR / PLAUR （112-303） Protein, His Tag 100ug UPR-H52H4-100ug
特徴
- 背景
- Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87.
- PLAUR contains three UPAR/Ly6 domains.
- U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain.
- PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1.
- PLAUR / UPAR acts as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation.
- U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.
- 特徴
- This protein carries a polyhistidine tag at the C-terminus.
- The protein has a calculated MW of 23.2 kDa.
- The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
- 容量：100ug
- Source：Human uPAR (112-303), His Tag (UPR-H52H4) is expressed from human 293 cells (HEK293). It contains AA Ser 112 - Arg 303 (Accession # Q03405-1).
- Species Reactivity：Human
- Host：HEK293
- Tag：C-10×His
- Exp Region：Ser 112 - Arg 303
- Format：Powder
- Conjugate：Unconjugated
- Swiss-Prot：Q03405-1
- Protein ID：NP_002650.1
- Endotoxin：1.0 EU per μg
- Purity：90%
- Buffer：PBS, pH7.4
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