The CA125, also known as the MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy.
The CA 125 molecule is almost certainly a glycoprotein with a predominance of O-linkages.
It is heterogeneous with regard to both size and charge, most likely due to continuous deglycosylation of side chains during its life-span in bodily fluids.
It exists as a very large complex (perhaps as much as 4 million daltons) under natural conditions.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 29.9 kDa.
The protein migrates as 44-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Rhesus macaque CA125 (12664-12920), His Tag (CA5-R52H3) is expressed from human 293 cells (HEK293). It contains AA Gly 12664 - Val 12920 (Accession # XP_015296314.1).
