B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein, CD antigen CD272.
BTLA contains one Ig-like V-type (immunoglobulin-like) domain.
As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response.
BTLA / CD272 can interact with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, and interact with TNFRSF14/HVEM.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 40.5 kDa.
The protein migrates as 48-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量:25ug
Source:Biotinylated Human BTLA (31-134), Fc,Avitag (BTA-H82F8) is expressed from human 293 cells (HEK293). It contains AA Lys 31 - Thr 134 (Accession # Q7Z6A9).
Species Reactivity:Human
Host:HEK293
Tag:C-Fc & C-Avi
Exp Region:Lys 31 - Thr 134
Format:Powder
Conjugate:Biotin-labeled
Swiss-Prot:Q7Z6A9
Endotoxin:1.0 EU per μg
Purity:95%
Buffer:Tris with Glycine, Arginine and NaCl, pH7.5