Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family.
Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin.
Both MPF and the cleaved form of mesothelin are N-glycosylated.
Mesothelin / MSLN can interacts with MUC16.
The membrane-anchored forms of MSLN may play a role in cellular adhesion.
MPF potentiates megakaryocyte colony formation in vitro.
特徴
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 37.8 kDa.
The protein migrates as 42-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：200ug
Source：Biotinylated Human Mesothelin (296-600), His,Avitag (MSN-H82E7) is expressed from human 293 cells (HEK293). It contains AA Glu 296 - Thr 600 (Accession # AAH09272.1).
