Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A) is also known as Fibroblast growth factor-inducible immediate-early response protein 14 (FN14 or FGF-inducible 14), Tweak-receptor, CD antigen CD266.
TNFRSF12A contains one TNFR-Cys repeat.
TNFRSF12A is highly expressed in heart, placenta and kidney.
TNFRSF12A is receptor for TNFSF12/TWEAK, and is weak inducer of apoptosis in some cell types.
TNFRSF12A / FN14 promotes angiogenesis and the proliferation of endothelial cells.
特徴
This protein carries a human IgG1 Fc tag at the N-terminus.
The protein has a calculated MW of 32.5 kDa.
The protein migrates as 32-45 kDa under reducing (R) condition, and 55-80 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human TWEAK R, Fc Tag (TNA-H526a) is expressed from human 293 cells (HEK293). It contains AA Glu 28 - Trp 79 (Accession # AAH02718).
