B18R is a type I interferon (IFN)-binding protein and it is encoded by the B18R open reading frame in the WR (Western Reserve) strain of vaccinia virus, which contains two Ig-like C2-type domains and one Ig-like V-type domain.
B18R exists in a soluble and a membrane-bound form.
As a type I IFN receptor, B18R counteracts the antiviral effects of host IFN-alpha/beta.
Also, B18R acts as a soluble IFN-alpha receptor and thus inhibits the interaction between host IFN-alpha and its receptor.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 40.3 kDa.
The protein migrates as 50-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：50ug
Source：Vaccinia Virus B18R, His Tag (B1R-H52H6) is expressed from human 293 cells (HEK293). It contains AA His 20 - Glu 351 (Accession # P25213).
