Syndecan-1 (SYND1 or SDC1) is also known as CD antigen CD138, is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family.
The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein.
The syndecan-1 / SDC1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins.
It is a useful marker for plasma cells, but only if the cells tested are already known to be derived from blood.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 52.0 kDa.
The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.
仕様
容量：200ug
Source：Biotinylated Human Syndecan-1, Fc,Avitag (SY1-H82F3) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Gly 254 (Accession # P18827-1).
