Signal-regulatory protein gamma (SIRPG or SIRP-gamma) is also known as CD172 antigen-like family member B (CD172g), Signal-regulatory protein beta-2 (SIRPB2), is a single-pass type I membrane protein.
SIRPG is expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells.
SIRPG interacts with CD47.
On binding with CD47, CD172g mediates cell-cell adhesion.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 63.7 kDa.
The protein migrates as 67-85 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human SIRP gamma, Fc Tag (SIG-H5253) is expressed from human 293 cells (HEK293). It contains AA Glu 29 - Ser 364 (Accession # AAH64532).
