Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family.
Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney.
Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4.
Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
特徴
This protein carries a llama IgG2b Fc tag at the C-terminus.
This protein contains a furin-like convertase cleavage site, 355-RQYR-358, and will be partially processed into N and C-terminal fragment with calculated MW of 38.1 kDa and 50.5 kDa respectively.
The protein migrates as 40 kDa, 60 kDa and 100-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Cynomolgus Glypican 3, Llama IgG2b Fc Tag, low endotoxin (GP3-C5259) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - His 559 (Accession # XP_005594665.1).
Species Reactivity：Cynomolgus
Host：HEK293
Tag：C-LlamaFc(LlamaIgG2b)
Exp Region：Gln 25 - His 559
Format：Powder
Conjugate：Unconjugated
Protein ID：XP_005594665.1
Endotoxin：0.01 EU per μg
Purity：90%
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
