Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family.
Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney.
Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4.
Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
特徴
This protein carries a polyhistidine tag at the C-terminus.
This protein contains a furin-like convertase cleavage site, 355-RQYR-358, and will be processed into N and C-terminal fragment with calculated MW of 38.1 kDa and 24.6 kDa respectively.
The N and C‑terminal fragment as 42 kDa and 66-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Cynomolgus Glypican 3, His Tag (GP3-C5225) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - His 559 (Accession # XP_005594665.1).
