Lipopolysaccharide-binding protein (LBP),a member of the BPI/LBP/Plunc superfamily, BPI/LBP family, is detected in blood serum.
LBP plays a role in the innate immune response.
Alao,LBP can bind to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and act as an affinity enhancer for CD14, facilitating its association with LPS.
Furthermore, LBP is able to promote the release of cytokines in response to bacterial lipopolysaccharide.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 52.8 kDa.
The protein migrates as 62 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human Lipopolysaccharide, His Tag (LBP-H52H5) is expressed from human 293 cells (HEK293). It contains AA Ala 26 - Val 481 (Accession # P18428-1 (I465F)).
