Prominin-1 is also known as CD133, Antigen AC133, PROM1, PROML1 and MSTP061.
Is used as marker for hematopoietic stem and progenitor cells (HSPC) for somatic stem cell isolation.
May play a role in cell differentiation, proliferation and apoptosis .
Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells.
During early retinal development acts as a key regulator of disk morphogenesis.
Involved in regulation of MAPK and Akt signaling pathways.
In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 97.2 kDa.
The protein migrates as 90-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：20ug
Source：Human CD133, His Tag (CD3-H52H4) is expressed from human 293 cells (HEK293). It contains AA Gly 20 - His 865 (Accession # O43490-1).
