83-3824-15 Human DLL4 Protein, Fc Tag 100ug DL4-H5259-100ug
特徴
- 背景
- Delta-like protein 4 (DLL4) is also known as Drosophila Delta homolog 4 (Delta4), which contains one DSL domain and eight EGF-like domains.
- DLL4 is expressed in vascular endothelium.
- DLL4 is involved in the Notch signaling pathway as Notch ligand, which can activates NOTCH1 and NOTCH4.
- DLL4 is involved in angiogenesis and negatively regulates endothelial cell proliferation and migration and angiogenic sprouting.
- DLL4 can bind to Notch-1 and Notch-4.
- 特徴
- This protein carries a human IgG1 Fc tag at the C-terminus.
- The protein has a calculated MW of 80.9 kDa.
- The protein migrates as 95-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
- 容量：100ug
- Source：Human DLL4, Fc Tag (DL4-H5259) is expressed from human 293 cells (HEK293). It contains AA Ser 27 - Pro 524 (Accession # NP_061947.1).
- Species Reactivity：Human
- Host：HEK293
- Tag：C-Fc
- Exp Region：Ser 27 - Pro 524
- Format：Powder
- Conjugate：Unconjugated
- Swiss-Prot：Q9NR61
- Protein ID：NP_061947.1
- Endotoxin：0.01 EU per μg
- Purity：95%
- Buffer：100 mM Glycine, 150 mM NaCl, 25 mM Arginine, 50 mM Tris, pH7.5
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