Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily.
TNFRSF17 contains one TNFR-Cys repeat.
TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes.
TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL.
TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity.
TNFRSF17 can activate NF-kappa-B and JNK.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 32.0 kDa.
The protein migrates as 35-44 kDa under reducing (R) condition, and 60-75 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
仕様
容量：25ug
Source：FITC-Labeled Human BCMA, Fc Tag (Cat. No. BCA-HF254) is expressed from human HEK293 cells. It contains AA Met 1 - Ala 54 (Accession # Q02223-1). It is the FITC labeled form of Human BCMA, Fc Tag (Cat. No. BC7-H5254).
