Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily.
TNFRSF17 contains one TNFR-Cys repeat.
TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes.
TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL.
TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity.
TNFRSF17 can activate NF-kappa-B and JNK.
特徴
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 9.6 kDa.
The protein migrates as 12 kDa and 15-17 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：25ug
Source：Biotinylated Human BCMA, His,Avitag (BCA-H82E4) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 54 (Accession # Q02223-1).
