83-3822-83 Human CD4 / LEU3 Protein, His Tag （MALS verified） 1mg LE3-H5228-1mg
特徴
- 背景
- T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3.
- CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain.
- CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction.
- CD4 induces the aggregation of lipid rafts.
- CD4 is a primary receptor used by HIV-1 to gain entry into host T cells.
- HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors.
- Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.
- 特徴
- This protein carries a polyhistidine tag at the C-terminus.
- The protein has a calculated MW of 41.5 kDa.
- The protein migrates as 47-54 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
- 容量：1mg
- Source：Human CD4, His Tag (LE3-H5228) is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Trp 390 (Accession # AAH25782).
- Species Reactivity：Human
- Host：HEK293
- Tag：C-6×His
- Exp Region：Lys 26 - Trp 390
- Format：Powder
- Conjugate：Unconjugated
- Swiss-Prot：P01730
- Protein ID：AAH25782
- Endotoxin：1.0 EU per μg
- Purity：90%
- Buffer：PBS, pH7.4
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