Butyrophilin subfamily 1 member A1 (BTN1A1) is also known as BTN, which is a member of the immunoglobulin superfamily and the major protein associated with fat droplets in the milk.
BTN1A1 may have a cell surface receptor function.
The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families.
Furthermore, BTN1A1 regulates the amount of lipids and size of droplets expressed in milk and inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 50.6 kDa.
The protein migrates as 55-66 kDa under reducing (R) condition, and 116-130 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human BTN1A1, Fc Tag (BT1-H5253) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Arg 242 (Accession # AAH96312).
Species Reactivity：Human
Host：HEK293
Tag：C-Fc
Exp Region：Ala 27 - Arg 242
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：Q13410
Protein ID：AAH96312
Endotoxin：1.0 EU per μg
Purity：95%
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
